r - creating one new data frame applying one function over existing one -

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i'm trying create new data frame using existing 1 data in pairs

targetid    a1           a2           b1      b2      cg00000108 0.94483140 0.959417300 0.94427000 0.956393400  cg00000292 0.83331720 0.836168900 0.75568530 0.869691000  cg00001594 0.00000000 0.009319287 0.00318779 0.001852309  cg00003298 0.01775547 0.034981820 0.03380106 0.116663900  cg00003345 0.55442110 0.542106600 0.54762020 0.624028200  cg00004055 0.10287610 0.107147500 0.09293073 0.106663000

the idea 1 data frame results of subtraction between pairs,so getting finallythree final columns

targetid a1-a2 b1-b2

i tried apply have no enough programming skills in r how function begin subtraction

thanks in advance

how simply:

with(d, data.frame(targetid, a1-a2, b1-b2))

where d data frame.


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